Pages

Friday, September 6, 2024

.. track 13.. of disc one.. track 13.. of disc one.. of the four disc-set of 'simply soundtracks'.. a BMG company.. 2017 Union Square Ltd. .. .. track 13.. of disc one.. is the official, quintessential instrumental of.. the very, very, very conclusion of the film 'Mission Impossible: the Beginning: Chapter two' .. the text on the screen of the very, very, very end of this movie.. this text being.. "Mission: succeeded.... Ethan Hunt: a Winner" .. .. .. .. (Ethan Hunt is still Tom Cruise) .. .. $3.. stochastic disturbance terms.. issue #823 paul dini / joe benitez poison ivy pamela isley kate moss megan d. iseult winona ryder angelina "Gia" jolie.. stochastic disturbance terms.. $3..

.. actor Kevin Bacon: ..".. It's what Havok looks like.. hanno.. I don't think he actually.. looks like Kenneth Connell.. it's like.. something about Kenneth Connell looking like Havok.. it's just.. something about Kenneth Connel's face.. in the very first Jim Shooter issues.. it's just.. what if.. Havok doesn't.. actually.. look like Kenneth Connell.. do you know the person who Havok actually does look like.. he looks just like Kendra Leigh Wilkinson's son, Hank Baskett IV.. Havok looks just like him.. how Hank Baskett IV looks like right now.. he looks.. just like.. Havok.. the same face.. the same.. exact.. face.." .. .. .. .. $3.. stochastic disturbance terms.. issue #823 paul dini / joe benitez poison ivy pamela isley kate moss megan d. iseult.. stochastic disturbance terms.. $3..

.. Gerry Duggan Lorna Dane (Gal Godot): ..".. It's like.. you honestly.. can't.. Havok (Hanno Alexander Raudsepp).. you honestly.. can't.. get angry like that.. with those obscene vocabulary.. words.. I mean.. it's supposed to.. it is-.. I mean.. it's impossible.. it actually.. is.. impossible for you.. to get angry.. with that obscene vocabulary.. You don't. You see, Havok (Hanno Alexander Raudsepp).. You don't. It's not the normal thing. (.. okay.. the quote 'It's not the normal thing' is probably most likely from Henry James's 'The Golden Bowl'..).. I mean.. You don't. Havok (Hanno Alexander Raudsepp). Get angry.. with those words.. with those terror-words. It's that.. you have rages in which you say.. rational things.. or even basic, very, very basic arguments against.. The Voices.. there is something so beyond-alien about the terror-word vocabulary of your rages.. Havok (Hanno Alexander Raudsepp).. I wish it had never HAPPENED.. because I know you feel abnormal like Ted Bundy because of that.. Havok (Hanno Alexander Raudsepp).. I mean.. it's like.. what if.. that old standby.. It's not you?.. Havok (Hanno Alexander Raudsepp)?" .. .. .. .. $3.. stochastic disturbance terms.. issue #823 paul dini / joe benitez poison ivy pamela isley kate moss megan d. iseult.. stochastic disturbance terms.. $3..

.. Lady Deathstryke (Tiffany Fallon): ..".. I don't think that roaches.. smaller insects similar to roaches.. I don't think they live.. in our.. reality.. I mean.. for real.. I think they live in a parallel reality.. a parallel reality we can see and perceive and maybe even like actually physically interact with.. in our home kitchen.. like.. maybe that's the philosophy of Bishop Berkeley that comes into play.. wait.. it's by studying the life and work of James Joyce that you find out about the specific philosophy of Bishop Berkeley.." .. .. .. .. $3.. stochastic disturbance terms.. issue #823 paul dini / joe benitez poison ivy pamela isley kate moss megan d. iseult.. stochastic disturbance terms.. $3..

Tuesday, September 3, 2024

.. Story by Alex Hammer...... copy-and-pasted from.. from.. www.dailymail.com.uk/ .. or.. or also.. the URL... https://www.msn.com/en-ca/health/other/father-creates-drug-to-treat-son-s-incurable-neurological-disorder/ar-AA1pS5Xh#:~:text=Story%20by%20Alex%20Hammer%20For%20Dailymail.Com%20%E2%80%A2%2038m.%20A%20father

Father creates drug to treat son's 'incurable' rare neurological disorder: 'I couldn't let him die' By Alex Hammer For Dailymail.Com Published: 13:39 EDT, 2 September 2024 | Updated: 14:19 EDT, 2 September 2024 e-mail 58 shares 65 View comments A father has developed a new drug to treat his young son's slow progressing neurodegenerative disorder. Terry Pirovolakis, 44, received regulatory approval for the clinical treatment this past December - first, in hopes of saving the life of his six-year-old son, Michael, and now to help all affected by the rare disease, Fox News reported. Spastic paraplegia 50 (SPG50) affects children's development, leading to cognitive impairment, muscle weakness, and paralysis over the course several years. Affecting fewer than 100 worldwide, the disease often ends in death, usually before a patient reaches 30. Such a fate awaited Michael before his dad, an IT director in Toronto, Canada stepped in. He emptied his life savings to start researching potential cures rooted in gene therapy, reading countless journals on the subject. Meeting with experts as well, he soon signed a contract to start a gene therapy program, consisting of injecting cerebral spinal fluid into the patient's back. After years of lab work, the treatment started to take, and on December 30, 2021, the government moved it forward. Terry Pirovolakis, 44, received regulatory approval for the clinical treatment this past December - first, in hopes of saving the life of his six-year-old son, Michael, and now to help all affected by the rare disease + 8 View gallery Terry Pirovolakis, 44, received regulatory approval for the clinical treatment this past December - first, in hopes of saving the life of his six-year-old son, Michael, and now to help all affected by the rare disease The rare disease affects children's development, leading to cognitive impairment, muscle weakness, and paralysis over the course several years + 8 View gallery The rare disease affects children's development, leading to cognitive impairment, muscle weakness, and paralysis over the course several years TRENDING Researchers reveal ultra-processed foods that surge heart attack risk 247k viewing now This diet could transform your health in three months 84.2k viewing now Scientists identify 'golden rule' for intermittent fasting success 42.6k viewing now 'On March 24, 2022, my son was the first person to ever get treated with gene therapy at SickKids in Toronto,' Pirovolakis, a father of three, told Fox News in detailing his medical odyssey. 'They said he'd never walk or talk, and would need support for the rest of his life,' he recalled of the 2018 diagnosis. 'They told us to just go home and love him - and said he would be paralyzed from the waist down by age 10, and quadriplegic by age 20,' he continued. 'We then liquidated our life savings, refinanced our home and paid a team at the University of Texas Southwestern Medical Center to create a proof of concept to start Michael's gene therapy.' This all happened within the span of a month, the doting dad said - recalling how he flew to Washington, D.C., for a gene therapy conference and met with several experts. He then went overseas, visiting the National Institutes of Health at the University of Cambridge, where scientists have been studying the disease. After months of testing, Pirovolakis and the experts he enlisted saw some success - with the therapy seen stopping the debilitating disease's progression in mice and human cells. Pirovolakis went on to work with a small drug company in Spain to manufacture the drug, which is injected directed into the patient's spine - paving the way for the procedure to one day become commonplace. Pirovolakis realized the disease was slowly affecting his son a year and half after he was born, when he saw he was having difficulty lifting his head + 8 View gallery Pirovolakis realized the disease was slowly affecting his son a year and half after he was born, when he saw he was having difficulty lifting his head When his son was diagnosed in 2018, Pirovolakis was told the boy would be paralyzed from the waist down by the age of 10 and quadriplegic by the age of 20. Georgia Pirovolakis is seen here with her son + 8 View gallery When his son was diagnosed in 2018, Pirovolakis was told the boy would be paralyzed from the waist down by the age of 10 and quadriplegic by the age of 20. Georgia Pirovolakis is seen here with her son He also detailed how the disease was slowly stealing his son's movement for the first year and half of his life, and how he only realized something was amiss when he noticed Michael was having difficulty lifting his head. It took months of doctors' appointments, physiotherapy, and even genetic testing to discern the cause - a process he billed as an '18-month diagnostic odyssey' predating his quest for a cure. Time was of the essence for him and Michael, however, as those stricken with SPG50 more often than not die by the time they reach their 20s. 'The prognosis varies from person to person, but it's generally a progressive condition, meaning symptoms can become more severe over time,' Texas Department of State Health Service epidemiologist Eve Elizabeth Penney told Fox News. 'Over time, these symptoms can worsen, making it hard for affected individuals to walk and perform daily activities,' she added. Since there is no cure currently, families are forced to manage symptoms through a combination of physical, occupational, and speech therapy, along with medications designed to lessen side effects like seizures. In the US currently, there is no treatment for SPG50 that is approved by the Food and Drug Administration. Now six, the boy is showing signs of improvement, his father said - though the treatment remains costly + 8 View gallery Now six, the boy is showing signs of improvement, his father said - though the treatment remains costly In Canada, Michael was the first to receive his father's one-time treatment, after Pirovolakis quit his job and started a nonprofit in California to devote himself to the cause. The company - named Elpida Therapeutics, after the Greek word for 'hope' - now has five employees and 20 consultants, with Michael now on the mend. Since being treated, the youngster's condition seems to have stabilized, his dad said. Michael is now able to use a device to communicate with his family and caregivers The same can be said for three others who were able to receive the remaining doses from Pirovolakis' first batch, as the drug still costs about $1million to make for each child. 'When I heard that no one was going to do anything about it, I had to - I couldn't let them die,' Pirovolakis said. 'We decided that we had to help other kids.' Pirovolakis opened a Phase 2 study in the U.S., which treated the three children in 2022. Among them was 6-month-old Jack Lockard, whose mother, Rebekah Lockard, told Fox News that the treatment works. 'Jack has thrived since then,' said the mom of two, whose other child, 3-year-old Naomi, has the disease as well, said. Pirovolakis opened a Phase 2 study in the U.S., which treated the three children in 2022. Among them was 6-month-old Jack Lockard, seen above in the lap of mom Rebekah Lockard + 8 View gallery Pirovolakis opened a Phase 2 study in the U.S., which treated the three children in 2022. Among them was 6-month-old Jack Lockard, seen above in the lap of mom Rebekah Lockard 'He is sitting independently, banging toys together, drinking from a straw cup and working really hard on crawling.' 'Doctors and therapists share the same sentiment,' she added. 'The treatment works!' Despite it being approved, big pharmaceutical companies have been slow to manufacture the drug, with several firms rejecting the prospect when proposed, Pirovolakis said 'No investor is going to give you money to treat a disease that is not going to make money,' he said. 'That's the dilemma we're in.' As he searches for grants and investors, parents are forced to pay out of pocket. 'The treatment is here, just literally sitting in a refrigerator, ready to go,' Lockard said, as the drug is now poised to undergo clinical trial at the National Institutes of Health. 'Doctors are ready. There just isn't enough money to make it happen.' Pirovolakis said 'time is of the essence,' noting that eight doses have already been flown to the US. 'We want to make sure the trial moves on and these kids get treated.' Pirovolakis - seen here with his family - will now see his drug undergo a clinical trial at the National Institutes of Health, as big pharmaceutical companies have been slow to sign off on making the drug + 8 View gallery Pirovolakis - seen here with his family - will now see his drug undergo a clinical trial at the National Institutes of Health, as big pharmaceutical companies have been slow to sign off on making the drug 'We were told he would never speak or walk, and that he will have severe developmental delays. I just couldn't accept that fate for my child,' Pirovolakis said of his son + 8 View gallery 'We were told he would never speak or walk, and that he will have severe developmental delays. I just couldn't accept that fate for my child,' Pirovolakis said of his son Pirovolakis said that when his son was diagnosed, he was told the boy would be paralyzed from the waist down by the age of ten and quadriplegic by the age of 20. 'We were told he would never speak or walk, and that he will have severe developmental delays. I just couldn't accept that fate for my child,' he said. 'The technology to cure our children is already here. I hope that someone with immense wealth - and more importantly, the vision and influence - will step in.' The Phase 3 study for SPG50 will be conducted at the National Institutes of Health in November. Fox News

Monday, September 2, 2024

.. Story by Daniel Trainor.. I'm really not sure about this article.. there was no blurring on "The Girls next Door" on StarTV.. It just seems.. is this really true?.. copy-and-pasted from the URL... .. .. https://www.msn.com/en-us/tv/news/holly-madison-claims-she-was-never-told-naked-uncensored-girls-next-door-footage-would-be-on-dvd/ar-AA1ncjJ9

47K Followers Holly Madison Claims She Was Never Told Naked, Uncensored ‘Girls Next Door’ Footage Would Be on DVD Story by Daniel Trainor • 7mo • 2 min read Holly Madison Claims She Was Never Told Naked, Uncensored ‘Girls Next Door’ Footage Would Be on DVD 'The Girls Next Door' star Holly Madison told Bethenny Frankel about the 'ridiculous' experience of naked footage from the show being distributed, allegedly without her consent Published |Updated Daniel Trainor Holly Madison has gotten candid about allegedly being taken advantage of during her time on Playboy Mansion reality series The Girls Next Door. During a conversation on the Just B podcast with host Bethenny Frankel, who has been leading the "reality reckoning" charge, Madison opened up about her own mistreatment. AI PCs built for business Intel vPro AI PCs built for business Ad "We were being filmed shooting our pictorials and things like that, so there was nudity," Madison explained. "We just assumed, 'Oh, they can't show that on E!. It has to be blurred.'" Except, there was a major problem. "We were never told that the uncensored footage was going to be put on DVDs," Madison claimed, "or aired in foreign markets and things like that." The Girls Next Door aired on E! for six seasons from 2005 to 2010, showing a peek into the lives of Playboy founder Hugh Hefner and his gaggle of girlfriends, and every season was later distributed digitally. Bridget Marquardt, Holly Madison, Hugh Hefner, Zoe Gregory, Sheila LeVell, Cristal Camden and Izabella St. James in 2003. Denise Truscello/WireImage Bridget Marquardt, Holly Madison, Hugh Hefner, Zoe Gregory, Sheila LeVell, Cristal Camden and Izabella St. James in 2003. Denise Truscello/WireImage © Provided by The Messenger "People even show pirated, uncensored versions on YouTube, and YouTube won't take it down," Madison alleged. "It's ridiculous." LAS VEGAS, NEVADA - MARCH 29: Holly Madison poses during a portrait shoot at Casa RaLuMaCa on March 29, 2023 in Las Vegas, Nevada. Denise Truscello/WireImage LAS VEGAS, NEVADA - MARCH 29: Holly Madison poses during a portrait shoot at Casa RaLuMaCa on March 29, 2023 in Las Vegas, Nevada. Denise Truscello/WireImage © Provided by The Messenger Now, all Madison can do — with the help of agitators like Frankel — is be vigilant in a call for change. "I think there should definitely be some regulations," Madison said. "People should know exactly, in their contract, what they're signing. If any nudity gets caught on camera, is it going to be used? Where is it going to be used?" Ad The Messenger Visit The Messenger Margot Robbie Responds to ‘Barbie’ Oscars Snub: ‘There’s No Way to Feel Sad’ Trump Said He Had The ‘Best Border’ In US History. Here’s The Truth. Cole Sprouse Doesn’t Regret ‘Missing Out’ on High School: ‘Sounds Horrible for Everybody’ (Exclusive) Ad Sponsored Content